Introduction.: During the course of pregnancy, women are particularly prone to microbial infections that are not potentially life-threatening; however, they may pose a serious threat to developing foetus. A woman can prevent infection either by being in contact with the pathogen during childhood or by acquiring immunity through vaccination. The viruses that are threatening to pregnant women include, among others, cytomegalovirus and rubella virus. These pathogens may cause congenital infections that can lead to a number of birth defects or even stop the development of the foetus. Therefore, an early diagnosis and prevention is crucial as far as pregnant women are concerned. Objectives. The aim of the study was to evaluate cytomegalovirus and rubella antibody titers in women of childbearing potential. Objectives.: The aim of the study was to evaluate cytomegalovirus and rubella antibody titers in women of childbearing potential. Material and methods: In order to assess the titer of IgG class antibodies to cytomegalovirus and rubella in women of childbearing age, 42 blood serum samples collected from women aged between 20–25 years were examined. Determination of the presence and quantity of the specific antibodies was performed by utilising the NovaLisaTM sets and ELISA method. Results: The study indicated the presence of IgG antibodies to cytomegalovirus in 61.9% of the examined women and IgG antibodies to rubella virus in 97.6% of those examined. Conclusions: 1. Approximately 40% of the examined had no antibody against cytomegalovirus, which indicates the absence of a previous contact with CMV. 2. A high degree of immunization against rubella was observed among women at child-bearing age.