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• Hospital variation in surgical outcomes for gastric cancer: the impact of case-mix and treatment across a global cohort. Sander J.M. van Hootegem, Margrietha van der Linde, Marcel A. Schneider, Jeesun Kim, Felix Berlth, Yutaka Sugita, Peter P. Grimminger, Gian Luca Baiocchi, Giovanni De Manzoni, Maria Bencivenga, Suzanne S. Gisbertz, Souya Nunobe, Han-Kwang Yang, Christian A. Gutschow, Sjoerd M. Lagarde, Hester F. Lingsma, Bas P.L. Wijnhoven, The GastroBenchmark & GASTRODATA consortiums [m.in.] [AUT.] WOJCIECH POLKOWSKI, KAROL RAWICZ-PRUSZYŃSKI. Gastric Cancer [online] 2026 vol. 29 nr 2 s. 424-432, bibliogr. poz. 33, [przeglądany 19 stycznia 2026]. Dostępny w: https://link.springer.com/article/10.1007/s10120-025-01696-6. DOI: 10.1007/s10120-025-01696-6
  07.04.2026 19:35 • 2026
• Regional disparities in access to coordinated health care in Poland: development and application of an accessibility index. [AUT. KORESP.] MARLENA J. PIEKUT, [AUT.] JOLANTA A. PACIAN. BMC Health Serv. Res. [online] 2026 vol. 26 nr 1 [art. nr] 399, s. 1-13, bibliogr. poz. 49, [przeglądany 23 lutego 2026]. Dostępny w: https://link.springer.com/article/10.1186/s12913-026-14220-y. DOI: 10.1186/s12913-026-14220-y
  07.04.2026 19:30 • 2026
• Immunopathogenesis of multiple sclerosis - mechanisms of autoimmunity, neuroinflammation and strategies of treatment. [AUT.] GRZEGORZ KUREC, OLIWIA BURDAN, WIKTORIA TOCHMAN, KLAUDIA ŻÓRAW, [AUT. KORESP.] FILIP K. GAJEWSKI, [AUT.] URSZULA GAWRYŚ, ANNA JAMROZ-WIŚNIEWSKA. J. Pre-Clin. Clin. Res. [online] 2026 vol. 20 nr 1 s. 21-27, bibliogr. poz. 48, [przeglądany 18 lutego 2026]. Dostępny w: https://www.jpccr.eu/Immunopathogenesis-of-multiple-sclerosis-mechanisms-of-autoimmunity-nneuroinflammation,217936,0,2.html. DOI: 10.26444/jpccr/217936
  07.04.2026 19:27 • 2026
• The prevalence and long-term response to calcium channel blockers in patients with pulmonary arterial hypertension and positive vasoreactivity test - results of multicenter national registry (BNP-PL). [AUT. KORESP.] MICHAŁ PIŁKA, [AUT.] SZYMON DAROCHA, MARCIN WALIGÓRA, GRZEGORZ KOPEĆ, MICHAŁ FLORCZYK, ADAM TORBICKI, TATIANA MULAREK-KUBZDELA, ANNA SMUKOWSKA-GORYNIA, EWA LEWICKA, EWA MROCZEK, ŁUKASZ CHRZANOWSKI, PIOTR BŁASZCZAK, BEATA KUŚMIERCZYK, KATARZYNA PTASZYŃSKA, KATARZYNA MIZIA-STEC, EWA MALINOWSKA, MAŁGORZATA PEREGUD‑POGORZELSKA, MICHAŁ TOMASZEWSKI, WOJCIECH JACHEĆ, ILONA SKOCZYLAS, ZBIGNIEW GĄSIOR, AGNIESZKA PAWLAK, MIŁOSZ JAGUSZEWSKI, GRZEGORZ GRZEŚK, KATARZYNA BETKIER-LIPIŃSKA, PIOTR PRUSZCZYK, KATARZYNA WIDEJKO, JUDYTA WINOWSKA-JÓZWA, MARCIN KURZYNA. Orphanet J. Rare Dis. [online] 2026 vol. 21 nr 1 [art. nr] 119, s. 1-10, bibliogr. poz. 26, [przeglądany 7 kwietnia 2026]. Dostępny w: https://link.springer.com/article/10.1186/s13023-026-04250-4. DOI: 10.1186/s13023-026-04250-4
  07.04.2026 19:22 • 2026
• The evolution of ethical and legal regulations of drug research. [AUT. KORESP.] AGNIESZKA POLAK, [AUT.] ANNA ZAGAJA, MARIOLA DROZD. Drug Discov. Today [online] 2026 [art. nr] 104653, s. 1-24, bibliogr. poz. 129, [przeglądany 7 kwietnia 2026]. Dostępny w: https://www.sciencedirect.com/science/article/pii/S1359644626000589. DOI: 10.1016/j.drudis.2026.104653
  07.04.2026 19:12 • 2026
• Rituximab in a desensitization protocol as a rescue therapy in severe nephrotic syndrome - a case report. [AUT.] AGATA BUKOSKA, [AUT. KORESP.] ALEKSANDRA RYMARZ, [AUT.] FILIP WANTOCH-REKOWSKI, BEATA BIENIAŚ, JOLANTA MAŁYSZKO. J. Nephrol. [online] 2026 [art. nr] aajaf023, s. 1-4, bibliogr, [przeglądany 7 kwietnia 2026]. Dostępny w: https://academic.oup.com/joneph/advance-article/doi/10.1093/joneph/aajaf023/8571496. DOI: 10.1093/joneph/aajaf023
  07.04.2026 18:58 • 2026
• Mirabegron in patients with age-related macular degeneration treated for overactive bladder: a study protocol for a prospective observational non-randomized trial. [AUT.] LUCIA AMBROSIO, MAURIZIO CAMMALLERI, SERENA PANARIELLO, GIANLUIGI CALIFANO, ARIANNA SCALA, GIOVANNI IMPROTA, ANTONIO PISANI, ROBERT REJDAK, IRENEUSZ OSTROWSKI, LUCA FILIPPI, PAOLA BAGNOLI, [AUT. KORESP.] MASSIMO DAL MONTE, MARIO DAMIANO TORO. Front. Med. [online] 2026 vol. 13 [art. nr] 1761473, s. 1-7, bibliogr. poz. 30, [przeglądany 7 kwietnia 2026]. Dostępny w: https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2026.1761473/full. DOI: 10.3389/fmed.2026.1761473
  07.04.2026 18:47 • 2026
• In-hospital mortality among orthopedic trauma patients during and outside the COVID-19 pandemic: a nationwide population-based analysis of 2.67 million hospitalizations in Poland. [AUT.] MARIUSZ JOJCZUK, [AUT. KORESP.] KATARZYNA NAYLOR, [AUT.] KAMIL FILIPEK, IWONA DOLLIVER, KATARZYNA TOBOREK, [AUT. KORESP.] KRZYSZTOF GONIEWICZ. Arch. Orthop. Trauma Surg. [online] 2026 vol. 146 nr 1 [art. nr] 132, s. 1-9, bibliogr. poz. 35, [przeglądany 7 kwietnia 2026]. Dostępny w: https://link.springer.com/article/10.1007/s00402-026-06275-7. DOI: 10.1007/s00402-026-06275-7
  07.04.2026 18:44 • 2026
• Hyrtl’s fissure - a rare congenital temporal bone anomaly. [AUT.] OSKAR ROSIAK, [AUT. KORESP.] ANNA WAŚNIEWSKA-WŁODARCZYK, [AUT.] WIESŁAW KONOPKA, MARCIN SZYMAŃSKI. Folia Morphol. [online] 2026 vol. 85 [art. nr] e01726042, s. 1-6, bibliogr, [przeglądany 7 kwietnia 2026]. Dostępny w: https://journals.viamedica.pl/folia_morphologica/article/view/110328. DOI: 10.5603/fm.110328
  07.04.2026 18:39 • 2026
• Nomogram-based risk classification for predicting response to metastasis-directed stereotactic body radiotherapy in PSMA PET-staged oligorecurrent prostate cancer (PORTAL): an international, retrospective cohort study. [AUT. KORESP.] TIMO F. W. SOETERIK, [AUT.] MARCIN MISZCZYK, MAX PETERS, MATEUSZ BILSKI, GIULIO FRANCOLINI, PIETRO GARLATTI, LUCA NICOSIA, FILIPPO ALONGI, MĀRIS MEŽECKIS, JUSTYNA KOCIOŁEK, CARLO GRECO, TOMASZ TECHMAŃSKI, ELINE H. HUELE, FREDERIK R. TEUNISSEN, PAULIEN G. WESTHOFF, WESSEL VIS, MARIE A. D. HAVERKORT, JOCHEM R. N. VAN DER VOORT VAN ZYP, MARTIJN P. W. INTVEN, JOANNE M. VAN DER VELDEN, SHAHROKH F. SHARIAT, WIETSE S.C. EPPINGA. Lancet Oncol. 2026 vol. 27 nr 3 s. 383-392, bibliogr. poz. 30. DOI: 10.1016/s1470-2045(25)00717-x
  07.04.2026 15:51 • 2026
• Psychodermatology: from historic concepts to contemporary clinical practice. [AUT.] KATARZYNA PAWLIKOWSKA-ŁAGÓD, AGNIESZKA POLAK, [AUT. KORESP.] ANDRZEJ GRZYBOWSKI. Clin. Dermatol. 2026 vol. 44 nr 2 s. 299-304, bibliogr. DOI: 10.1016/j.clindermatol.2026.01.011
  07.04.2026 15:42 • 2026
• The use of medical imaging and modern technologies in coordinated patient care. [AUT. KORESP.] BARTOSZ PŁASKA, [AUT.] RAFAŁ PATRYN, NATALIA GRUSZKIEWICZ, BARTOSZ ŚWIERK, AGNIESZKA KOWALSKA-OLCZYK, MICHAŁ SEKUŁA. J. Pre-Clin. Clin. Res. [online] 2026 vol. 20 nr 1 s. 28-34, bibliogr. poz. 38, [przeglądany 4 lutego 2026]. Dostępny w: https://www.jpccr.eu/The-use-of-medical-imaging-and-modern-technologies-in-coordinated-patient-care,217065,0,2.html. DOI: 10.26444/jpccr/217065
  07.04.2026 15:37 • 2026

Najnowsze rekordy ze streszczeniem

• Immunopathogenesis of multiple sclerosis - mechanisms of autoimmunity, neuroinflammation and strategies of treatment. [AUT.] GRZEGORZ KUREC, OLIWIA BURDAN, WIKTORIA TOCHMAN, KLAUDIA ŻÓRAW, [AUT. KORESP.] FILIP K. GAJEWSKI, [AUT.] URSZULA GAWRYŚ, ANNA JAMROZ-WIŚNIEWSKA. J. Pre-Clin. Clin. Res. [online] 2026 vol. 20 nr 1 s. 21-27, bibliogr. poz. 48, [przeglądany 18 lutego 2026]. Dostępny w: https://www.jpccr.eu/Immunopathogenesis-of-multiple-sclerosis-mechanisms-of-autoimmunity-nneuroinflammation,217936,0,2.html. DOI: 10.26444/jpccr/217936
  ABSTRACT Introduction and objective: The aim of the review is to summarize current understanding of multiple sclerosis (MS) immunopathogenesis, focusing on Th17 cells, regulatory T cells, B lymphocytes, and innate immune components, while outlining contemporary and emerging therapeutic strategies Review methods: A literature search was conducted in PubMed and Scopus using the key words ‘multiple sclerosis’, ‘immunotherapy’, ‘autoimmunity’, ‘Th17 Cells’, and ‘B-Lymphocytes’ for publications occurring in publications between 2019–2025. A total of 412,560 articles were found – 173,450 were from PubMed and 239,110 from Scopus. After applying inclusion criteria to original research, reviews, book chapters, and editorials in English, 49 articles were selected for a narrative review. Over 96% of included studies were published within the last three years, reflecting a rapidly growing interest in the topic. Brief description of …
• The use of medical imaging and modern technologies in coordinated patient care. [AUT. KORESP.] BARTOSZ PŁASKA, [AUT.] RAFAŁ PATRYN, NATALIA GRUSZKIEWICZ, BARTOSZ ŚWIERK, AGNIESZKA KOWALSKA-OLCZYK, MICHAŁ SEKUŁA. J. Pre-Clin. Clin. Res. [online] 2026 vol. 20 nr 1 s. 28-34, bibliogr. poz. 38, [przeglądany 4 lutego 2026]. Dostępny w: https://www.jpccr.eu/The-use-of-medical-imaging-and-modern-technologies-in-coordinated-patient-care,217065,0,2.html. DOI: 10.26444/jpccr/217065
  Abstract Introduction and Objective. Coordinated care, launched nationwide in Poland in 2022, is a team-based model in which the general practitioner (GP) coordinates an individualized plan with specialists in nursing, dietetics, and other allied health carers to speed diagnostics, align treatment and monitor chronic disease. The aim of the review is to assess the technologies that enable this model – particularly diagnostic imaging, telemedicine and artificial intelligence (AI – together with data standards (HL7, DICOM; HIS/RIS/PACS), and the legal context. Review Methods. A narrative review conducted in line with PRISMA principles. Major databases were searched for publications on coordinated/integrated care and enabling technologies, screened titles/abstracts, assessed full texts for relevance to imaging, telemedicine and AI, and synthesized findings on interoperability standards and regulation. Brief description of the state of knowledge. …
• Molecular and physicochemical arrangement of chitosan–ibuprofen matrices for topical drug delivery on skin: preparation impact. [AUT. KORESP.] BARBARA GIEROBA, [AUT.] VLADYSLAV VIVCHARENKO, GRZEGORZ KALISZ, PAULINA KAZIMIERCZAK, OLENA MOZGOVA, MARYNA KHALAVKA, LIUDMYLA NOSACH, IZABELA S. PIĘTA, ROBERT NOWAKOWSKI, AGATA PRZEKORA, [AUT. KORESP.] ANNA SROKA-BARTNICKA. RSC Adv. [online] 2026 vol. 16 s. 15591-15608, bibliogr. poz. 95, [przeglądany 25 marca 2026]. Dostępny w: https://pubs.rsc.org/en/content/articlelanding/2026/ra/d6ra00296j. DOI: 10.1039/D6RA00296J
  Abstract Recent advances in modern medicine emphasize patient-centric and personalized therapeutic strategies, particularly for chronic and regenerative applications. Among emerging biomaterials, chitosan (CS) has gained considerable attention due to its biocompatibility, biodegradability, and antimicrobial properties, while its molecular weight strongly influences structural organization and interactions with active compounds. In this study, chitosan-based matrices—2% (w/v) low-molecular-weight CS, 4% (w/v) low-molecular-weight CS, and 2% (w/v) medium-molecular-weight CS—were developed and enriched with ibuprofen (IBU), a widely used non-steroidal anti-inflammatory drug, to improve topical delivery and reduce systemic side effects. The physicochemical properties of gelled thin films were investigated with emphasis on molecular arrangement, surface characteristics, and drug release behavior in phosphate-buffered saline. ATR-FTIR spectroscopy, contact angle measurements, and atomic force microscopy (AFM) were employed to evaluate structural and functional changes induced by IBU …
• Biochemical heterogeneity of endometriosis phenotypes revealed by FTIR analysis. [AUT. KORESP.] PIOTR OLCHA, [AUT.] WIESŁAW PAJA, MICHAŁ KĘPSKI, KRZYSZTOF PANCERZ, BARTOSZ KLEBOWSKI, ŁUKASZ NOWAKOWSKI, KRZYSZTOF GAŁCZYŃSKI, [AUT. KORESP.] JOANNA DEPCIUCH. J. Biophotonics [online] 2026 vol. 19 nr 3 [art. nr] e202500511, s. 1-10, bibliogr. poz. 42, [przeglądany 2 grudnia 2025]. Dostępny w: https://onlinelibrary.wiley.com/doi/10.1002/jbio.202500511. DOI: 10.1002/jbio.202500511
  Fourier-transform infrared (FTIR) spectroscopy was used to investigate molecular differences among peritoneal, ovarian, bowel endometriosis phenotypes and control tissues. Peritoneal lesions showed the most pronounced spectral changes in CH-stretching (2800–3000 cm−1) and 1000–1500 cm−1 regions, indicating protein and lipid alterations. Bowel lesions exhibited moderate but significant deviations, particularly in protein- and nucleic acid-associated bands, while ovarian lesions displayed subtler differences with increased lipid-related CH-stretching. Principal component analysis distinguished all phenotypes from controls, with peritoneal clustering most distinct, bowel intermediate, and ovarian partially overlapping. Key discriminative regions included phosphate vibrations (1080–1100, 1240–1250 cm−1), CH2 bending (~1450 cm−1), amide I (~1650 cm−1), and amide II (~1540 cm−1). Decision tree analysis identified phenotype-specific markers: 988 cm−1 (ovarian), 1101 cm−1 (bowel), 1544 cm−1 (peritoneal). Marker intensity correlated with tumor size and clinical scores, strongest …
• The outcomes of myeloid sarcoma in 64 pediatric patients and the impact of allogeneic hematopoietic stem cell transplantation on treatment results. [AUT. KORESP.] MAGDALENA SAMBORSKA, [AUT.] JOLANTA SKALSKA-SADOWSKA, JACEK WACHOWIAK, MAŁGORZATA CZOGAŁA, WALENTYNA BALWIERZ, SZYMON SKOCZEŃ, NATALIA BARTOSZEWICZ, JAN STYCZYŃSKI, TOMASZ OCIEPA, TOMASZ URASIŃSKI, GRAŻYNA WRÓBEL, KRZYSZTOF KAŁWAK, KATARZYNA MUSZYŃSKA-ROSŁAN, ANNA SZMYDKI-BARAN, IWONA MALINOWSKA, PAWEŁ ŁAGUNA, AGNIESZKA MIZIA-MALARZ, RENATA TOMASZEWSKA, TOMASZ SZCZEPAŃSKI, AGNIESZKA CHODAŁA-GRZYWACZ, GRAŻYNA KAROLCZYK, LUCYNA MACIEJKA-KEMBŁOWSKA, MARTA KOZŁOWSKA, NINELA IRGA-JAWORSKA, KATARZYNA MYCKO, WANDA BADOWSKA, KATARZYNA BOBEFF, WOJCIECH MŁYNARSKI, RADOSŁAW CHABER, JOANNA ZAWITKOWSKA, KATARZYNA DRABKO, KATARZYNA DERWICH. Children. [online] 2026 vol. 13 nr 3 [art. nr] 343, s. 1-10, bibliogr. poz. 32, [przeglądany 2 marca 2026]. Dostępny w: https://www.mdpi.com/2227-9067/13/3/343. DOI: 10.3390/children13030343
  Abstract Background: Myeloid sarcoma (MS) is a malignant extramedullary tumor that occurs in patients with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), or chronic myeloid leukemia (CML). The standard first-line treatment for MS is intensive chemotherapy according to the AML protocol, regardless of bone marrow involvement. The role of allogeneic hematopoietic stem cell transplantation (alloHSCT) in the treatment of pediatric patients with MS requires further investigation. The aim of the study was to evaluate treatment outcomes for MS in pediatric patients with a focus on assessing the impact of allogeneic hematopoietic stem cell transplantation (alloHSCT) on treatment efficacy. Material and Methods: The study included 64 patients aged 0 to 19 years from 15 pediatric oncology centers in Poland who were diagnosed with MS between 1998 and 2024. An Excel database …