1Wyszukiwanie od początku wyrazu:Wyraz preane znajdzie "preanestetyczny", ale anestetyczny nie znajdzie tego słowa (wyszukiwanie patrzy tylko na początek wyrazów)
-Wykluczanie słów (znak minus):Poprzedzenie wyrazu znakiem - znajdzie wszystkie tytuły NIE zawierające danego słowa, np. -onkologia znajdzie prace bez słowa "onkologia"
"Wyszukiwanie całych fraz (cudzysłów):Cudzysłów powoduje szukanie całych ciągów znaków w tej samej kolejności. Np. "Uniwersytet Medyczny" wyszuka tylko prace z dokładnie tą nazwą, podczas gdy wpisanie bez cudzysłowu może znaleźć "Medyczny Uniwersytet"
↕Nawigacja klawiaturą:Użyj / aby otworzyć wyszukiwanie, strzałek ↑↓ do nawigacji po wynikach, ENTER aby przejść do wybranej pozycji, lub ESC aby zamknąć okno
Porady BPP:Ładowanie porad...
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Biblioteka informuje, że dla artykułów z lat 2024-2025 uaktualniono punktację Impact Factor zgodnie z wartościami podanymi w bazie Journal Citation Reports edycja 2025
Biblioteka informuje, że dla artykułów z lat 2023-2024 uaktualniono punktację Impact Factor zgodnie z wartościami podanymi w bazie Journal Citation Reports edycja 2024
Biblioteka informuje, że dla artykułów z lat 2022-2023 uaktualniono punktację Impact Factor zgodnie z wartościami podanymi w bazie Journal Citation Reports edycja 2023
Mushroom-related intoxications pose a distinctive challenge for forensic medicine because early manifestations are non-specific, latency may be prolonged, and co-exposures can obscure the mechanism of death. This narrative review summarizes key toxic and psychoactive fungi and their principal compounds, spanning organ-toxic syndromes (amatoxins, orellanine) and functional neuropsychiatric intoxications—acute, predominantly functional effects causing impairment rather than organ failure (psilocybin/psilocin, ibotenic acid/muscimol). We propose an integrated diagnostic workflow combining exposure history, biochemical markers of organ injury, mycological assessment, and confirmatory toxicology. Particular emphasis is placed on postmortem interpretation: toxin instability and biotransformation, conjugation, matrix effects, postmortem redistribution (central vs. femoral blood), and postmortem fungal colonization that may alter analyte profiles or generate misleading metabolites. Because robust lethality thresholds are unavailable for most mushroom toxins, conclusions should rely on a multi-source synthesis of …
IntroductionThe objective of this consensus report is to provide practical, resource-stratified recommendations for the management of ovarian cancer in countries with limited resources, where direct application of international guidelines is often difficult. To address these challenges, recommendations were developed from a panel of international experts.MethodsThe panel met in New York in September/October 2022 during the International Gynecological Cancer Society congress and was composed of specialists from countries in Africa, Asia, Eastern Europe, Latin America, and the Middle East. The panel addressed 72 questions and provided recommendations for the diagnosis, staging, treatment, and surveillance of ovarian cancer. Consensus was defined as at least 75% of the voting members selecting a particular recommendation, whereas a majority vote was considered when one option garnered between 50% and …
Various drug classes target B-cell maturation antigen (BCMA) including chimeric antigen receptor T-cell (CAR-T) therapies, bispecific antibodies (bsAbs), and antibody-drug conjugates (ADCs). Outcomes with CAR-T and bsAb therapies in multiple myeloma (MM) have been affected by T-cell exhaustion, and abrogated expression/mutation of the BCMA target has been observed with anti-BCMA therapies. Optimal anti-BCMA sequencing strategies are needed to improve long-term clinical outcomes. We used data from multiple clinical studies of the ADC belantamab mafodotin (as monotherapy and combination regimens) to explore its impact on BCMA levels and binding (using electrochemiluminescence methodology) and T-cell/natural killer (NK) cell fitness (including cell counts, expression of functional markers), to determine whether belantamab mafodotin could be sequenced ahead of other BCMAtargeting therapies for MM. Levels of free soluble BCMA (sBCMA), measured at the best-confirmed response …
Background: Litsea cubeba, also known as mountain pepper, belongs to the Lauraceae family. It has been used as a traditional herbal medicine since approximately 600 A.D., for example, in traditional Chinese medicine to treat inflammation, headaches, and intoxication. Essential oil extracted from the fresh fruits of Litsea cubeba is a clear, oily liquid with various activities, including antimicrobial, antioxidant, anticancerous, anti-inflammatory, and anti-diabetic properties. L. cubeba fruit has demonstrated cytotoxic effects on human lung, liver, and oral cancer cells. It is also shown to inhibit tyrosinase and reduce melanin production in epidermal cells, leading to decreased discoloration and skin aging. Aim: The objective of this study is to provide a comprehensive report regarding the chemical composition and safety profiles, as well as the antioxidant and anti-tyrosinase activities, of Litsea cubeba …
Background/Objectives: Hemodialysis (HD) is the commonest life sustaining form of kidney replacement therapy in the world; however, this method of treatment have many adverse effects, and even a single HD session affects many organs, including the eyes. The aim of this study was to assess the effect of a single HD session on the ophthalmologic findings in patients with End-stage Renal Disease (ESRD). The second aim of the study was to examine the correlation of these changes with each other and between changes in systemic stressors related to the HD session. Methods: This was a single-center cross-sectional observational study conducted on 32 patients undergoing HD. Selected parameters of the anterior and posterior segment of the eye as well as systemic parameters were assessed before and after a single HD session. …
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