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• Metabolite profiling and anticancer evaluation of Iraqi Haloxylon articulatum Halophyte via LC-HRMS/MS, molecular docking, and ADMET analysis. [AUT.] JIHEN ABIDI, AMAL BEN HASSENA, RANIA BEN HMIDA, ŁUKASZ KULINOWSKI, ERDI CAN AYTAR, REYEDH R. AL-RASHIDI, [AUT. KORESP.] MOHAMED BOUAZIZ. Chem. Biodivers. [online] 2026 vol. 23 nr 2 [art. nr] e02619, s. 1-15, bibliogr. poz. 38, [przeglądany 4 lutego 2026]. Dostępny w: https://onlinelibrary.wiley.com/doi/10.1002/cbdv.202502619. DOI: 10.1002/cbdv.202502619
  05.02.2026 19:41 • 2026
• The impact of physical activity and nutritional patterns on phase angle in healthy adolescents. [AUT.] AGATA PRZYTUŁA, [AUT. KORESP.] PAWEŁ GLIBOWSKI, JOANNA POPIOŁEK-KALISZ. Nutrients [online] 2026 vol. 18 nr 3 [art. nr] 516, s. 1-13, bibliogr. poz. 30, [przeglądany 4 lutego 2026]. Dostępny w: https://www.mdpi.com/2072-6643/18/3/516. DOI: 10.3390/nu18030516
  05.02.2026 19:35 • 2026
• Predictors of severe outcomes in COVID-19: Evidence from real-world multicenter retrospective study (2020-2024). [AUT.] MAŁGORZATA WAJDOWICZ, KRYSTYNA DOBROWOLSKA, KINGA BRZDĘK, JAKUB JANCZURA, [AUT. KORESP.] DOROTA ZARĘBSKA-MICHALUK, [AUT.] ŁUKASZ SUPRONOWICZ, PIOTR RZYMSKI, MAGDALENA ROGALSKA, PIOTR CZUPRYNA, KRZYSZTOF TOMASIEWICZ, MARCIN HAWRO, MICHAŁ BRZDĘK. J. Clin. Med. [online] 2026 vol. 15 nr 3 [art. nr] 1207, s. 1-21, bibliogr. poz. 74, [przeglądany 4 lutego 2026]. Dostępny w: https://www.mdpi.com/2077-0383/15/3/1207. DOI: 10.3390/jcm15031207
  05.02.2026 19:32 • 2026
• Iodinated contrast media - from clinical use to environmental concern and treatment possibilities. [AUT.] KATARZYNA WRZESIŃSKA, MICHAŁ KWIATKOWSKI, PIOTR TEREBUN, DAWID ZARZECZNY, AGATA SUMARA, TOMOYUKI MURAKAMI, NOBUYA HAYASHI, FRANTISEK KRCMA, EVGENIA BENOVA, KAROL HENSEL, ZDENKO MACHALA, EMILIA FORNAL, [AUT. KORESP.] JOANNA PAWŁAT. Molecules [online] 2026 vol. 31 nr 3 [art. nr] 551, s. 1-33, bibliogr. poz. 107, [przeglądany 4 lutego 2026]. Dostępny w: https://www.mdpi.com/1420-3049/31/3/551. DOI: 10.3390/molecules31030551
  05.02.2026 19:28 • 2026
• Evaluation of the antimigraine and anti-neuroinflammatory activity of purified constituents of Petasites hybridus L. in a migraine-like pain model in mice. [AUT. KORESP.] ŁUKASZ KULINOWSKI, [AUT.] KATARZYNA TARGOWSKA-DUDA, DIANA PIETRZAK-MITURA, AKANKSHA MUDGAL, BENITA HRYĆ, ŁUKASZ KURACH, MACIEJ KORCZAK, JAKUB PIWOWARSKI, SIMON V. LUCA, BARBARA BUDZYŃSKA, KRYSTYNA SKALICKA-WOŹNIAK. Inflammopharmacology [online] 2026 s. 1-14, bibliogr. poz. 30, [przeglądany 4 lutego 2026]. Dostępny w: https://link.springer.com/article/10.1007/s10787-025-02107-z. DOI: 10.1007/s10787-025-02107-z
  05.02.2026 19:21 • 2026
• Modulation of the kynurenine pathway: a new approach for treating neurodegeneration. [AUT.] JULIA K. BANASZKIEWICZ, ANNA KUKIEŁKA, ELŻBIETA KUDYK, ŁUCJA J. WALCZAK, KATARZYNA WICHA-KOMSTA, MARIOLA HERBET, IWONA PIĄTKOWSKA-CHMIEL, GRZEGORZ NOWICKI, CARMEN E. MIELNIK, [AUT. KORESP.] TOMASZ KOCKI. Life [online] 2026 vol. 16 nr 2 [art. nr] 266, s. 1-42, bibliogr. poz. 221, [przeglądany 3 lutego 2026]. Dostępny w: https://www.mdpi.com/2075-1729/16/2/266. DOI: 10.3390/life16020266
  05.02.2026 18:51 • 2026
• Experimental models and translational strategies in neuroprotective drug development with emphasis on Alzheimer’s disease. [AUT.] PRZEMYSŁAW NIZIŃSKI, KAROLINA SZALAST, ANNA MAKUCH-KOCKA, KINGA PARUCH-NOSEK, MAGDALENA CIECHANOWSKA, [AUT. KORESP.] TOMASZ PLECH. Molecules [online] 2026 vol. 31 nr 2 [art. nr] 320, s. 1-44, bibliogr. poz. 359, [przeglądany 3 lutego 2026]. Dostępny w: https://www.mdpi.com/1420-3049/31/2/320. DOI: 10.3390/molecules31020320
  05.02.2026 18:47 • 2026
• Psychometric properties of the Polish version of the Mental Health Literacy Scale in nursing students: a cross-sectional study. [AUT. KORESP.] GRZEGORZ J. NOWICKI, [AUT.] OLIWIA ADAMCZYK, MACIEJ POLAK, MAGDALENA BRODOWICZ-KRÓL, MATEUSZ CYBULSKI, GRAŻYNA KOBUS, LUDMIŁA MARCINOWICZ, BARBARA ŚLUSARSKA. Front. Psychiatry [online] 2026 vol. 17 [art. nr] 1731025, s. 1-13, bibliogr. poz. 50, [przeglądany 2 lutego 2026]. Dostępny w: https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2026.1731025/full. DOI: 10.3389/fpsyt.2026.1731025
  05.02.2026 18:43 • 2026
• Volumetric differences in the brain in children with hypoxic-ischemic encephalopathy after therapeutic hypothermia: a review of MRI findings. [AUT. KORESP.] BARTŁOMIEJ SYZDOŁ, [AUT.] KAMILA ĆWIK, MAGDALENA WOŹNIAK. Pol. J. Radiol. [online] 2026 vol. 91 nr 1 s. e37-e44, bibliogr. poz. 44, [przeglądany 2 lutego 2026]. Dostępny w: https://www.polradiol.com/Volumetric-differences-in-the-brain-in-children-with-hypoxic-ischemic-encephalopathy,211222,0,2.html. DOI: 10.5114/pjr/211222
  05.02.2026 18:38 • 2026
• Diagnostic and therapeutic challenges of chest pain in children: a single center study. [AUT. KORESP.] WIKTORIA SIELWANOWSKA-LASEK, [AUT.] NATALIA GRYTA, WIKTORIA GOŁĘBIOWSKA, NATALIA WILCZEK, ERNEST FABER, AMELIA ADAMCZAK, ANNA BODAJKO-GROCHOWSKA, EWELINA WAWRYK-GAWDA, VIOLETTA OPOKA-WINIARSKA. Health Probl. Civiliz. [online] 2026 s. 1-22, bibliogr. poz. 24, [przeglądany 5 lutego 2026]. Dostępny w: https://hpc.edu.pl/Diagnostic-and-therapeutic-challenges-of-chest-pain-in-children-a-single-center-study,217305,0,2.html. DOI: 10.29316/hpc/217305
  05.02.2026 18:24 • 2026
• Competitive adsorption processes in mixed CTAB-alcohol systems at the surface of a liquid silver amalgam electrode (R-AgLAFE). [AUT. KORESP.] ALICJA PAWLAK, [AUT.] AGNIESZKA NOSAL-WIERCIŃSKA, MARIUSZ GROCHOWSKI, TERESA URBAN, ANNA SZABELSKA. Physicochem. Probl. Miner. Process. [online] 2026 vol. 62 nr 1 [art. nr] 216341, s. 1-15, bibliogr. poz. 37, [przeglądany 3 lutego 2026]. Dostępny w: https://www.journalssystem.com/ppmp/Competitive-adsorption-processes-in-mixed-CTAB-alcohol-systems-at-the-surface-of,216341,0,2.html. DOI: 10.37190/ppmp/216341
  05.02.2026 18:17 • 2026
• Combined positive score status in metastatic triple‑negative breast cancer patients treated with sacituzumab govitecan: associated clinical characteristics and testing patterns in a Central European cohort. [AUT. KORESP.] KAROLINA WINSKO‑SZCZĘSNOWICZ, [AUT.] MAŁGORZATA PIENIĄŻEK, ANNA POLAKIEWICZ-GILOWSKA, KUBECZKO MARCIN, MILOŠ HOLÁNEK, MIROSLAVA MALEJČÍKOVÁ, RENÁTA SOUMAROVÁ, HANA ŠTUDENTOVÁ, ALEKSANDRA KONIECZNA, AGNIESZKA MŁODZIŃSKA, JUSTYNA ŻUBROWSKA, MAJA LISIK-HABIB, ANIKA PĘKALA, DANIEL KREJČÍ, JAN ŠUSTR, IVETA KOLÁŘOVÁ, IWONA DANIELEWICZ, MAGDALENA SZYMANIK-RESKO, TOMASZ CISZEWSKI, LENKA RUSINOVÁ, BOGUMIŁA CZARTORYSKA-ARŁUKOWICZ, ALEKSANDRA ŁACKO, MICHAŁ JARZĄB, ZUZANA BIELČIKOVÁ, [AUT. KORESP.] RENATA PACHOLCZAK‑MADEJ, MIROSŁAWA PÜSKÜLLÜOĞLU. Clin. Transl. Radiat. Oncol. [online] 2026 s. 1-10, bibliogr. poz. 32, [przeglądany 3 lutego 2026]. Dostępny w: https://link.springer.com/article/10.1007/s12094-026-04236-5. DOI: 10.1007/s12094-026-04236-5
  05.02.2026 18:10 • 2026

Najnowsze rekordy ze streszczeniem

• Experimental models and translational strategies in neuroprotective drug development with emphasis on Alzheimer’s disease. [AUT.] PRZEMYSŁAW NIZIŃSKI, KAROLINA SZALAST, ANNA MAKUCH-KOCKA, KINGA PARUCH-NOSEK, MAGDALENA CIECHANOWSKA, [AUT. KORESP.] TOMASZ PLECH. Molecules [online] 2026 vol. 31 nr 2 [art. nr] 320, s. 1-44, bibliogr. poz. 359, [przeglądany 3 lutego 2026]. Dostępny w: https://www.mdpi.com/1420-3049/31/2/320. DOI: 10.3390/molecules31020320
  Neurodegenerative diseases (NDDs), including Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), are becoming more prevalent and still lack effective disease-modifying therapies (DMTs). However, translational efficiency remains critically low. For example, a ClinicalTrials.gov analysis of AD programs (2002–2012) estimated ~99.6% attrition, while PD programs (1999–2019) achieved an overall success rate of ~14.9%. In vitro platforms are assessed, ranging from immortalized neuronal lines and primary cultures to human-induced pluripotent stem cell (iPSC)-derived neurons/glia, neuron–glia co-cultures (including neuroinflammation paradigms), 3D spheroids, organoids, and blood–brain barrier (BBB)-on-chip systems. Complementary in vivo toxin, pharmacological, and genetic models are discussed for systems-level validation and central nervous system (CNS) exposure realism. The therapeutic synthesis focuses on AD, covering symptomatic drugs, anti-amyloid immunotherapies, tau-directed approaches, and repurposed drug classes that target …
• Balancing efficacy and toxicity in salvage brachytherapy and SBRT for radio-recurrent prostate cancer: insights beyond the UroGEC review. [AUT.] MATEUSZ BILSKI, JACEK FIJUTH, ŁUKASZ KUNCMAN. Technol. Cancer Res. Treat. 2026 vol. 25 s. 1-3, bibliogr. DOI: 10.1177/15330338261415791
  Salvage treatment for locally recurrent prostate cancer after primary radiotherapy remains a clinical challenge, with multiple modalities— including stereotactic body radiotherapy (SBRT), high-dose-rate (HDR) brachytherapy, and low-dose-rate (LDR) brachytherapy—competing for optimal use. The recent UroGEC expert review in Radiotherapy & Oncology provides a timely synthesis of available evidence and underscores the potential role of brachytherapy in this setting. Here, we contextualize these findings with recently published meta-analyses that expand the evidence base and refine our understanding of salvage outcomes. Updated analyses highlight significant differences across modalities: HDR brachytherapy achieves favorable disease control with low gastrointestinal toxicity, whereas LDR appears to offer superior relapse- free survival in selected subgroups at the cost of higher late genitourinary morbidity. By contrast, SBRT, although attractive for its non-invasiveness, demonstrates lower long-term relapse-free survival when …
• Serum 25-hydroxyvitamin D levels in breast cancer patients: a cross-sectional analysis by molecular tumor subtypes. [AUT.] DOROTA WEBER, ANDRZEJ STANISŁAWEK, ANNA IRZMAŃSKA-HUDZIAK, TERESA KULIK, [AUT. KORESP.] ANNA B. PACIAN, [AUT.] MONIKA BARYŁA-MATEJCZUK, MARTA ŁUCZYK, ROBERT ŁUCZYK. J. Clin. Med. [online] 2026 vol. 15 nr 2 [art. nr] 833, s. 1-16, bibliogr. poz. 30, [przeglądany 21 stycznia 2026]. Dostępny w: https://www.mdpi.com/2077-0383/15/2/833. DOI: 10.3390/jcm15020833
  Background: Vitamin D deficiency has been implicated in breast cancer pathogenesis and prognosis. However, the relationship between serum 25-hydroxyvitamin D [25(OH)D] levels and molecular breast cancer subtypes remains incompletely understood. Methods: This cross-sectional study included 168 women (89 breast cancer patients, 79 healthy controls) from Poland. Serum 25(OH)D was measured by electrochemiluminescence immunoassay. Blood samples were collected year-round, with 54% obtained during winter/spring months (October–March). Molecular subtypes (luminal A, luminal B, HER2-enriched, triple-negative) were classified by immunohistochemistry. Results: Mean 25(OH)D was 30 ± 13 ng/mL, with 55% showing insufficiency (<30 ng/mL). No significant differences were observed between patients and controls (p = 0.93). A borderline non-significant trend was observed across molecular subtypes (p = 0.055). HER2-enriched tumors showed descriptively higher concentrations (37.6 ng/mL, 95% CI: 29.5–45.8) compared to luminal A …
• Kinetics and mechanism of In(III) ions electroreduction on cyclically renewable liquid silver amalgam film electrode: significance of the active complexes of In(III) - acetazolamide. [AUT. KORESP.] AGNIESZKA NOSAL-WIERCIŃSKA, [AUT.] MARLENA MARTYNA, ALICJA PAWLAK, ALEKSANDRA BAZAN-WOŹNIAK, ROBERT PIETRZAK, SELEHATIN YILMAZ, SULTAN YAĞMUR KABAŞ, ANNA SZABELSKA. Molecules [online] 2023 vol. 28 nr 7 [art. nr] 2942, s. 1-15, bibliogr. poz. 33, [przeglądany 29 marca 2023]. Dostępny w: https://www.mdpi.com/1420-3049/28/7/2942. DOI: 10.3390/molecules28072942
  The results of kinetic measurements revealed an accelerating effect of acetazolamide (ACT) on the multistep In(III) ions electroreduction in chlorates(VII) on a novel, cyclically renewable liquid silver amalgam film electrode (R–AgLAFE). The kinetic and thermodynamic parameters were determined by applying the DC polarography, square-wave (SWV) and cyclic voltammetry (CV), as well as electrochemical impedance spectroscopy (EIS). It was shown that ACT catalyzed the electrode reaction (“cap-pair” effect) by adsorbing on the surface of the R–AgLAFE electrode. The catalytic activity of ACT was explained as related to its ability to form active In(III)- acetazolamide complexes on the electrode surface, facilitating the electron transfer process. The active complexes constitute a substrate in the electroreduction process and their different structures and properties are responsible for differences in the catalytic activity. The determined values …
• Global consensus for the screening, diagnosis, staging, treatment, and surveillance of ovarian cancer in areas of significant resource limitations: report from the International Gynecological Cancer Society consensus meeting. [AUT.] FERNANDO MALUF, [AUT. KORESP.] HENRIQUE A. HELBER, [AUT.] FRANCINNE TOSTES, LIGIA A. MALUF, JULIANA K. HELITO, RENATO MORETTI-MARQUES, GRAZIELA Z. DAL MOLIN, BRUNO ROBERTO B. AZEVEDO, DAVID I. ORTIZ, DAVID CANTU, AGNALDO L. SILVA FILHO, ANGELICA NOGUEIRA-RODRIGUES, REITAN RIBEIRO, GEORGIA F. CINTRA, GUSTAVO GUITMANN, ANDREIA CRISTINA DE MELO, EDUARDO PAULINO, GLAUCO BAIOCCHI, LEANDRO RESENDE, MICHELLE S. DE ALMEIDA, DIOCESIO A. DE ANDRADE, JULIO L. DE LA VEGA, FLORENCIA NOLL, FABIO FIN, ANDRE LOPES, MIGUEL E. CORREA, JOSEPH S. NG, DANIEL SANABRIA, GABRIEL RENDON, FERNANDO HEREDIA, ANA PAULA E. LOPES, MYRIAM B. MUSSI, MARCIN BOBIŃSKI, MILAGROS P. QUINTANILLA, JIMENA MEYMAR, DAVID ATALLAH, AUDREY TSUNODA. Front. Oncol. [online] 2025 vol. 15 [art. nr] 1677427, s. 1-7, bibliogr, [przeglądany 2 lutego 2026]. Dostępny w: https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1677427/full. DOI: 10.3389/fonc.2025.1677427
  IntroductionThe objective of this consensus report is to provide practical, resource-stratified recommendations for the management of ovarian cancer in countries with limited resources, where direct application of international guidelines is often difficult. To address these challenges, recommendations were developed from a panel of international experts.MethodsThe panel met in New York in September/October 2022 during the International Gynecological Cancer Society congress and was composed of specialists from countries in Africa, Asia, Eastern Europe, Latin America, and the Middle East. The panel addressed 72 questions and provided recommendations for the diagnosis, staging, treatment, and surveillance of ovarian cancer. Consensus was defined as at least 75% of the voting members selecting a particular recommendation, whereas a majority vote was considered when one option garnered between 50% and …