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• Chromatographic profiling of Alchemilla peristerica and A. crinita extracts in relation to their anti-HHV-1 activity. [AUT.] S[EBASTIAN] KANAK, M[ARCIN] KOLEŚNIK, Ł[UKASZ] ŚWIĄTEK, M.P. DYBEK, KATARZYNA DOS SANTOS SZEWCZYK. W: 12th International Symposium on Chromatography of Natural Products. Lublin, May 10-13, 2026. Abstr s. 45. Lublin 2026, Medical University of Lublin.
  23.05.2026 13:53 • 2026
• Comprehensive chromatographic profiling and bioactivity assessment of Alchemilla speciosa buser for dermatological applications. [AUT.] S[EBASTIAN] KANAK, K[ATARZYNA] KLIMEK, M[ARTA] OLECH, M[AŁGORZATA] MIAZGA-KARSKA, M.P. DYBEK, K[ATARZYNA] DOS SANTOS SZEWCZYK. W: 12th International Symposium on Chromatography of Natural Products. Lublin, May 10-13, 2026. Abstr s. 44. Lublin 2026, Medical University of Lublin.
  23.05.2026 13:50 • 2026
• Effect of plant growth regulators on the biochemical potential activity of extracts from Achillea ptarmica L. in vitro cultures. [AUT.] K. CZECH, A. SZOPA, W[IRGINIA] KUKUŁA-KOCH, A. GŁOWNIAK-LIPA, K. GAWEŁ-BĘBEN. W: 12th International Symposium on Chromatography of Natural Products. Lublin, May 10-13, 2026. Abstr s. 36, bibliogr. Lublin 2026, Medical University of Lublin.
  23.05.2026 13:46 • 2026
• Functional modulation of epithelial-mesenchymal transition and tumor microenvironment signalling by diosmetin in breast cancer in vitro model. [AUT.] MONIKA MICHALCZYK, JOANNA KUBIK, ALEKSANDRA JÓZEFCZYK, MAGDALENA IWAN, AGNIESZKA KORGA-PLEWKO. W: 12th International Symposium on Chromatography of Natural Products. Lublin, May 10-13, 2026. Abstr s. 43, bibliogr. Lublin 2026, Medical University of Lublin.
  23.05.2026 13:45 • 2026
• Materia medica opoliensis - a relational database integrating multi-system knowledge of natural medicinal resources and phytotherapy. [AUT.] Z. SKOTNICKI, R. BALWIERZ, T[OMASZ] BAJ. W: 12th International Symposium on Chromatography of Natural Products. Lublin, May 10-13, 2026. Abstr s. 35, bibliogr. Lublin 2026, Medical University of Lublin.
  23.05.2026 13:42 • 2026
• LC/MS profiling of phenolic compounds in leaves of Magnolia kobus DC. and evaluation of their antioxidant potential. [AUT.] ALDONA ADAMSKA-SZEWCZYK, GRAŻYNA ZGÓRKA. W: 12th International Symposium on Chromatography of Natural Products. Lublin, May 10-13, 2026. Abstr s. 34, bibliogr. Lublin 2026, Medical University of Lublin.
  23.05.2026 13:40 • 2026
• Linden inflorescences and elderflower as natural products with antiviral properties. [AUT.] M[AREK] RYBAK, A. KRAĆ, K[INGA] SALWA, A[NASTAZJA] BOGUSZEWSKA, M[ARCIN] KOLEŚNIK, K[AMILA] JAGLIŃSKA, B[EATA] POLAK. W: 12th International Symposium on Chromatography of Natural Products. Lublin, May 10-13, 2026. Abstr s. 31, bibliogr. Lublin 2026, Medical University of Lublin.
  23.05.2026 13:36 • 2026
• Geographical stability and environmental modulation of secondary metabolites in Marchantia polymorpha across Europe. [AUT.] F[ILIP] NOWACZYŃSKI, B[ENITA] HRYĆ, N. CRONBERG, A[GNIESZKA] LUDWICZUK. W: 12th International Symposium on Chromatography of Natural Products. Lublin, May 10-13, 2026. Abstr s. 28, bibliogr. Lublin 2026, Medical University of Lublin.
  23.05.2026 13:32 • 2026
• Chemical investigation of Heracleum ternatum fruits: LC-QTOF-MS/MS analysis and CPC isolation. [AUT.] L. UŠJAK, K[RYSTYNA] SKALICKA-WOŹNIAK, Ł[UKASZ] KULINOWSKI, M. NIKETIĆ, S. PETROVIĆ. W: 12th International Symposium on Chromatography of Natural Products. Lublin, May 10-13, 2026. Abstr s. 24, bibliogr. Lublin 2026, Medical University of Lublin.
  23.05.2026 13:30 • 2026
• Antiviral potential of natural products. [AUT.] Ł[UKASZ] ŚWIĄTEK, K[INGA] SALWA, A[NASTAZJA] BOGUSZEWSKA. W: 12th International Symposium on Chromatography of Natural Products. Lublin, May 10-13, 2026. Abstr s. 25, bibliogr. Lublin 2026, Medical University of Lublin.
  23.05.2026 13:30 • 2026
• Metabolic reprogramming of macrophages during infection: impact of antibiotics and natural products on amino acids, ceramides, and tca cycle intermediates. [AUT.] B[ENITA] HRYĆ, Ł[UKASZ] ŚWIĄTEK, K[INGA] SALWA, A[NASTAZJA] BOGUSZEWSKA, M[ARCIN] ZIOMEK, G[RZEGORZ] JANKOWSKI, R[AFAŁ] SAWICKI, E[LWIRA] SIENIAWSKA. W: 12th International Symposium on Chromatography of Natural Products. Lublin, May 10-13, 2026. Abstr s. 41, bibliogr. Lublin 2026, Medical University of Lublin.
  23.05.2026 13:23 • 2026
• An evidence-based digital course for training caregivers in respiratory infection prevention among vulnerable groups. [AUT.] BEATA DOBROWOLSKA, KINGA ZDUNEK, STEFANIA CHIAPPINOTTO, CHIARA MOREAL, MARIA MONTSERRAT SOLA POLA, LUCIA BENITO ARACIL, AYSEL ÖZSABAN, AYSUN BAYRAM, NEVENKA KREGAR VELIKONJA, SABINA KRSNIK, ALVISA PALESE, Protecting You & Others project consortium. W: 4th Central European Nursing Conference. Ostrava, 20th May 2026 [online]. [Abstr.] s. 12, [przeglądany 23 maja 2026]. Dostępny w: https://eduo.osu.cz/entities/publication/7b8831c4-5e7f-4249-8233-a40b4fc02ecb. Ostrava 2026.
  23.05.2026 13:17 • 2026

Najnowsze rekordy ze streszczeniem

• Defining effect size thresholds for OR, RR, and η² in physiotherapy studies. [AUT.] GRZEGORZ ZIELIŃSKI. Stats [online] 2026 vol. 9 nr 3 [art. nr] 49, s. 1-11, bibliogr. poz. 40, [przeglądany 22 maja 2026]. Dostępny w: https://www.mdpi.com/2571-905X/9/3/49. DOI: 10.3390/stats9030049
  Abstract (1) Background: Effect size interpretation in physiotherapy research varies across statistical models, hindering comparability between studies using linear, logistic, and variance-based analyses. Unified, discipline-specific thresholds are needed to harmonise interpretation and support consistent sample size planning in clinical trials. The aim is to estimate physiotherapy-specific reference values for odds ratio (OR), relative risk (RR), and η2/ηp2 based on empirically established thresholds for Cohen’s d (0.1, 0.4, and 0.8). (2) Methods: Cohen’s d values were transformed into corresponding effect size metrics using deterministic algebraic relationships. Specifically, OR, RR, and η2 were derived from Cohen’s d under selected baseline risks (p0 = 0.1, 0.2, and 0.5). Calculations were performed in R 4.3.1 assuming equal group sizes and homogeneity of variances. (3) Results: OR thresholds were 1.20 (small), 2.07 (medium), and 4.27 …
• Extracts from the edible mushroom Sparassis crispa: nematicidal, antimicrobial, and antiviral properties supporting its functional food potential. [AUT. KORESP.] MARTA ZIAJA-SOŁTYS, [AUT.] BARBARA RAJTAR, ŁUKASZ ŚWIĄTEK, ANNA BIERNASIUK, KATARZYNA DOS SANTOS SZEWCZYK, SEBASTIAN GRANICA, ANDRZEJ PARZONKO, DANIEL ZALEWSKI, ŁUCJA SMOLARSKA, SEBASTIAN SKOWRON, ANNA BOGUCKA-KOCKA. Foods [online] 2026 vol. 15 nr 9 [art. nr] 1559, s. 1-29, bibliogr. poz. 66, [przeglądany 4 maja 2026]. Dostępny w: https://www.mdpi.com/2304-8158/15/9/1559. DOI: 10.3390/foods15091559
  Abstract Sparassis crispa (cauliflower mushroom) is an edible medicinal fungus known for its diverse array of bioactive metabolites. Despite its established nutritional and pharmacological relevance, its antimicrobial, antiviral, and antiparasitic activities remain insufficiently investigated. In the present study, extracts of the fruiting bodies of S. crispa were prepared using four solvents (water, 60% ethanol, methanol–acetone–water [3:1:1], and 1% acetic acid) and evaluated for their chemical composition and broad-spectrum biological activities. UHPLC-MS/MS profiling revealed distinct metabolite profiles among the extracts, including identification of nucleosides such as adenosine and methylthioadenosine. All extracts exhibited nematicidal activity against Rhabditis sp. nematodes in a dose-dependent manner, with the 60% ethanol extract being the most potent (LD50 = 4.2 mg/mL). In antiviral assays, the water extract partially inhibited Coxsackievirus B3 (CVB3) replication, reducing infectious titers by …
• Ubiquitous computing and smart systems in the treatment of psychiatric and neurological disorders - a narrative review. [AUT.] DARIUSZ MIKOŁAJEWSKI, [AUT. KORESP.] EMILIA MIKOŁAJEWSKA, [AUT.] JOLANTA MASIAK, EWELINA PANAS, URSZULA ROGALLA-ŁADNIAK. Electronics [online] 2026 vol. 15 nr 8 [art. nr] 1627, s. 1-35, bibliogr. poz. 175, [przeglądany 5 maja 2026]. Dostępny w: https://www.mdpi.com/2079-9292/15/8/1627. DOI: 10.3390/electronics15081627
  This bibliometric study examines the role of ubiquitous computing and intelligent systems in the treatment of mental and neurological disorders. Ubiquitous computing integrates computational intelligence into everyday environments, enabling seamless monitoring and support of patients. Intelligent systems, including wearable devices, environmental sensors, and mobile health applications, collect real-time data on behavior, physiology, and environmental factors. These systems support early detection of symptom changes, adherence to treatment, and crisis prediction through context-aware analysis. Artificial intelligence (AI) processes the collected data to generate personalized therapeutic feedback and notify healthcare providers when intervention is needed. In mental health care, intelligent environments can monitor mood, sleep, and social interaction patterns, providing valuable objective information about mental health status. In the case of neurological conditions such as Parkinson’s disease or epilepsy, intelligent systems facilitate movement …
• Proteomic analysis of tear film in dogs and cats: emerging biomarkers of cognitive dysfunction and neurodegenerative disorders. [AUT. KORESP.] DAGMARA WINIARCZYK, [AUT.] MATEUSZ WINIARCZYK. Animals [online] 2026 vol. 16 nr 6 [art. nr] 930, s. 1-15, bibliogr. poz. 53, [przeglądany 1 kwietnia 2026]. Dostępny w: https://www.mdpi.com/2076-2615/16/6/930. DOI: 10.3390/ani16060930
  Abstract Cognitive dysfunction and neurodegenerative disorders represent an increasing clinical challenge in aging dogs and cats, while objective and minimally invasive biomarkers for early detection and disease monitoring remain limited. Tear film is a biologically active fluid reflecting both local and systemic processes and offers a practical, non-invasive source of potential biomarkers in geriatric veterinary patients. Proteomic analyses of canine and feline tear film have revealed a complex protein composition, including molecules involved in inflammation, oxidative stress, immune regulation, and cellular homeostasis—processes implicated in neurodegeneration. However, growing evidence from human and veterinary research emphasizes the importance of CNS-specific and mechanistically informative biomarkers, such as markers of axonal injury, synaptic degeneration, and glial activation, which may provide a more precise framework for interpreting peripheral proteomic alterations. This review summarizes current knowledge …
• Molecular analysis of inherited disorders of cornification in polish patients show novel variants and functional data and provokes questions on the significance of secondary findings. [AUT. KORESP.] KATARZYNA WERTHEIM-TYSAROWSKA, [AUT.] KATARZYNA OSIPOWICZ, KATARZYNA WOŹNIAK, JUSTYNA SAWICKA, ADRIANNA MIKA, ANNA KUTKOWSKA-KAŹMIERCZAK, KATARZYNA NIEPOKÓJ, AGNIESZKA SOBCZYŃSKA-TOMASZEWSKA, BARTŁOMIEJ WAWRZYCKI, ALDONA PIETRZAK, ROBERT ŚMIGIEL, BARTOSZ WOJTAŚ, BARTŁOMIEJ GIELNIEWSKI, ALICJA SZABELSKA-BERESEWICZ, JOANNA ZYPRYCH‑WALCZAK, AGNIESZKA M. RYGIEL, ALICJA DOMASZEWICZ, NATALIA BRAUN-WALICKA, ALICJA GRABARCZYK, SYLWIA RZOŃCA-NIEWCZAS, LIDIA RUSZKOWSKA, MATEUSZ DAWIDZIUK, DOMINIK DOMAŃSKI, TOMASZ GAMBIN, MONIKA JACKIEWICZ, KATARZYNA DUK, BARBARA DOROŻKO, OREST SZCZYGIELSKI, NATALIA KRZEŚNIAK, BARTŁOMIEJ H. NOSZCZYK, EWA OBERSZTYN, JOLANTA WIERZBA, ARTUR BARCZYK, JENNIFER CASTANEDA, ANNA ECKERSDORF-MASTALERZ, ANNA JAKUBIUK-TOMASZUK, PAWEŁ WŁASIENKO, ILONA JASZCZUK, ALEKSANDRA JEZELA-STANEK, JAKUB KLAPECKI, MICHEL VAN GEEL, CEZARY KOWALEWSKI, JERZY BAL, ANTONI GOSTYŃSKI. Orphanet J. Rare Dis. [online] 2024 vol. 19 [art. nr] 413, s. 1-14, bibliogr. poz. 43, [przeglądany 20 listopada 2024]. Dostępny w: https://ojrd.biomedcentral.com/articles/10.1186/s13023-024-03395-4. DOI: 10.1186/s13023-024-03395-4
  Abstract Background The Mendelian Disorders of Cornification (MeDOC) comprise a large number of disorders that present with either localised (palmoplantar keratoderma, PPK) or generalised (ichthyoses) signs. The MeDOC are highly heterogenic in terms of genetics and phenotype. Consequently, diagnostic process is challenging and before implementation of the next generation sequencing, was mostly symptomatic, not causal, which limited research on those diseases. The aim of the study was to genetically characterise a cohort of 265 Polish patients with MeDOC and to get insight into the skin lesions using transcriptome and lipid profile analyses. Results We detected causal variants in 85% (226/265) patients. In addition to the primary gene defect, a pathogenic variant in another gene involved in MeDOC pathology was identified in 23 cases. We found …