Abstract Introduction. Stroke is a rare condition in children, affecting 1–2 per 100 paediatric patients annually. Despite the low incidence, it is the leading cause of neurological disorders in this age group. Case Report. An 8-year-old girl was admitted to the emergency department with reduced muscle strength, drooping of the left corner of the mouth, and sensory disturbances. Imaging studies revealed intracerebral haemorrhagic foci surrounded by oedema in the right frontal lobe, subarachnoid haemorrhagic foci, as well as ischemic changes in the left frontal lobe. Empiric pharmacotherapy with anti-coagulants, anti-oedematous agents and antibiotics was applied. After treatment and rehabilitation, substantial improvement was observed. Conclusions. Management of strokes in paediatric patients poses significant challenges. Absence of well-established guidelines and randomized clinical trials in this age group often necessitates empiric therapy, which proved to be highly effective in the presented case. Key words pharmacotherapy, paediatric neurology, paediatric stroke, haemorrhagic stroke