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• Evaluation of some 3-substituted rhodanine derivatives as anti-candida agents with ferric reducing capacity. [AUT.] AGATA PANETH, ALEKSANDRA SZOPA, [AUT. KORESP.] KAROLINA WOJTUNIK-KULESZA, [AUT.] JOANNA LACHOWICZ-RADULSKA, ANNA SEREFKO, IZABELA KORONA-GŁOWNIAK, ANNA ONISZCZUK, KATARZYNA DZITKO, [AUT. KORESP.] NAZAR TROTSKO. Appl. Sci. [online] 2026 vol. 16 nr 10 [art. nr] 4759, s. 1-27, bibliogr. poz. 78, [przeglądany 12 maja 2026]. Dostępny w: https://www.mdpi.com/2076-3417/16/10/4759. DOI: 10.3390/app16104759
  18.05.2026 11:22 • 2026
• Quality without compromise: a propensity score-matched analysis of robotic versus laparoscopic surgery for locally advanced colorectal cancer. [AUT.] MARCIN KUBIAK, WOJCIECH GÓRSKI, MLAK RADOSŁAW, ZUZANNA DĄBROWSKA, JOLANTA SADO, KINGA BIELARSKA. Cancers [online] 2026 vol. 18 nr 10 [art. nr] 1601, s. 1-20, bibliogr. poz. 33, [przeglądany 30 stycznia 2026]. Dostępny w: https://www.mdpi.com/2072-6694/18/10/1601. DOI: 10.3390/cancers18101601
  18.05.2026 11:22 • 2026
• Phytochemical profile and selective anticancer activity of Colocasia esculenta (L.) Schott leaf extracts. [AUT.] IZABELA BIELECKA, DOROTA NATORSKA-CHOMICKA, W[IOLETA] DOŁOMISIEWICZ, ARLINDO RODRIGUES FORTES, KATARZYNA KLIMEK, KATARZYNA DOS SANTOS SZEWCZYK. Biol. Life Sci. Forum [online] 2026 vol. 63 nr 1 s. 22-23, 4th International Scientific Conference on Plant Biodiversity and Sustainability, 19-21 May 2025 [Abstr.], [przeglądany 18 maja 2026]. Dostępny w: https://www.mdpi.com/2673-9976/63/1/1.
  18.05.2026 10:42 • 2026
• Anti-aging potential of cannabinoids as an aspect of promoting longevity. [AUT.] EMILIA SŁOŃ, DOROTA KOWALCZUK. Biol. Life Sci. Forum [online] 2026 vol. 63 nr 1 s. 30-31, 4th International Scientific Conference on Plant Biodiversity and Sustainability, 19-21 May 2025 [Abstr.], [przeglądany 18 maja 2026]. Dostępny w: https://www.mdpi.com/2673-9976/63/1/1. DOI: 10.3390/blsf2026063001
  18.05.2026 10:35 • 2026
• Guz brunatny jako rzadka patologiczna zmiana szczęk. (Index: brown tumor, giant cells, mandibular tumor.). [AUT.] ANNA GAWĘDA, ALEKSANDRA BEDNARCZYK, JULIA RYBIENIK, KAROLINA USOWSKA. W: Kongres Polskiego Towarzystwa Chirurgii Stomatologicznej i Szczękowo-Twarzowej. Lublin, 8-10 maja 2025. [Streszcz.] s. 29-30, [Tekst równol. w jęz. ang.].
  18.05.2026 10:23 • 2025
• Rola miR-455, miR-1271 i miR-486 w patogenezie niedożywienia i kacheksji nowotworowej - przegląd mechanizmów molekularnych. [AUT.] MACIEJ DUBAJ, KAROL BIGOSIŃSKI, IWONA HOMA-MLAK, TERESA MAŁECKA-MASSALSKA. W: VII Ogólnopolska Konferencja Naukowa „Choroby nowotworowe wyzwaniem dla nauk medycznych w XXI wieku”. [B. m.], 15 maja 2026 r. [online]. Red. Izabela Mołdoch-Mendoń, Paulina Pomajda. Abstr s. 38-39, [przeglądany 18 maja 2026]. Dostępny w: https://bc.wydawnictwo-tygiel.pl/publikacja/0F9601D7-F8FF-A31B-118A-FE03A0517B2E. Lublin 2026, Fundacja na rzecz promocji nauki i rozwoju TYGIEL, 978-83-68503-19-7.
  18.05.2026 10:09 • 2026
• Cząsteczki H19, PVT1 i TUG1 jako modulatory dysfunkcji mitochondrialnej i stresu oksydacyjnego w kacheksji nowotworowej. [AUT.] MACIEJ DUBAJ, KAROL BIGOSIŃSKI, IWONA HOMA-MLAK, TERESA MAŁECKA-MASSALSKA. W: VII Ogólnopolska Konferencja Naukowa „Choroby nowotworowe wyzwaniem dla nauk medycznych w XXI wieku”. [B. m.], 15 maja 2026 r. [online]. Red. Izabela Mołdoch-Mendoń, Paulina Pomajda. Abstr s. 21-22, [przeglądany 18 maja 2026]. Dostępny w: https://bc.wydawnictwo-tygiel.pl/publikacja/0F9601D7-F8FF-A31B-118A-FE03A0517B2E. Lublin 2026, Fundacja na rzecz promocji nauki i rozwoju TYGIEL, 978-83-68503-19-7.
  18.05.2026 10:07 • 2026
• Biological activities and therapeutic potential of soy isoflavones: a focus on anticancer activity. [AUT.] MACIEJ KWIECIŃSKI, BARTŁOMIEJ KWIATKOWSKI, WERONIKA ZIOMEK, WERONIKA BOMBA, [AUT. KORESP.] PAULA WRÓBLEWSKA-ŁUCZKA. Mol. Biol. Rep. [online] 2026 vol. 53 nr 1 [art. nr] 769, s. 1-24, bibliogr. poz. 104, [przeglądany 18 maja 2026]. Dostępny w: https://link.springer.com/article/10.1007/s11033-026-11922-8. DOI: 10.1007/s11033-026-11922-8
  18.05.2026 09:58 • 2026
• Association of miR-133a with microalbuminuria in patients with resistant arterial hypertension and chronic kidney disease. [AUT. KORESP.] ROBERT T. BŁASZCZYK, [AUT.] ALICJA PETNIAK, JACEK BOGUCKI, JANUSZ KOCKI, ŁUKASZ WIŚNIOWSKI, ANDRZEJ GŁOWNIAK. Med. Sci. Monit. [online] 2026 vol. 32 [art. nr] e952860, s. 1-10, bibliogr. poz. 33, [przeglądany 15 maja 2026]. Dostępny w: https://medscimonit.com/abstract/index/idArt/952860. DOI: 10.12659/MSM.952860
  18.05.2026 09:57 • 2026
• The role of thromboelastometry in the prevention of complications in DIEP flap breast reconstruction. [AUT.] MACIEJ BISKUPSKI, SERGEY ANTONOV, GRZEGORZ WILHELM, MACIEJ ŁĄCZYK, ZOFIA M. GÓRECKA, MAREK MAJEWSKI, AGNIESZKA SUROWIECKA, PAULINA MERTOWSKA, EWELINA GRYWALSKA. Ann. Agric. Environ. Med. [online] 2026 s. 1-6, bibliogr. poz. 24, [przeglądany 18 maja 2026]. Dostępny w: https://www.aaem.pl/The-role-of-thromboelastometry-in-the-prevention-of-complications-in-DIEP-flap-breast,220865,0,2.html. DOI: 10.26444/aaem/220865
  18.05.2026 09:54 • 2026
• Coronary-subclavian steal syndrome as a unique and overlooked cause of ST-T segment elevation myocardial infarction. Perfect cooperation between an invasive cardiologist and a vascular surgeon - a case report. [AUT. KORESP.] MACIEJ DOBOSZ, [AUT.] MICHAŁ SOJKA, PAWEŁ BINKO, JAN SOBSTYL, AGNIESZKA WOJTKOWSKA, TOMASZ ZAPOLSKI. Acta Angiol. [online] 2026 vol. 32 [art. nr] e01026007, s. 1-5, bibliogr, [przeglądany 15 maja 2026]. Dostępny w: https://journals.viamedica.pl/acta_angiologica/article/view/110210. DOI: 10.5603/aa.110210
  18.05.2026 09:53 • 2026
• Uromodulin and tryptophan metabolite clearance in hemodialyzed patients. [AUT. KORESP.] IZABELA ZAKROCKA, [AUT.] MAŁGORZATA KOZIOŁ, MARTA WIĘCKOWSKA-DEROŃ, SYLWIA BOCZKOWSKA, RENATA KLOC, TOMASZ KOCKI, ALINA OLENDER, EWA M. URBAŃSKA, WOJCIECH ZAŁUSKA, ANDREAS KRONBICHLER. J. Clin. Med. [online] 2026 vol. 15 nr 10 [art. nr] 3743, s. 1-16, bibliogr. poz. 39, [przeglądany 15 maja 2026]. Dostępny w: https://www.mdpi.com/2077-0383/15/10/3743. DOI: 10.3390/jcm15103743
  18.05.2026 09:49 • 2026

Najnowsze rekordy ze streszczeniem

• Proteomic analysis of tear film in dogs and cats: emerging biomarkers of cognitive dysfunction and neurodegenerative disorders. [AUT. KORESP.] DAGMARA WINIARCZYK, [AUT.] MATEUSZ WINIARCZYK. Animals [online] 2026 vol. 16 nr 6 [art. nr] 930, s. 1-15, bibliogr. poz. 53, [przeglądany 1 kwietnia 2026]. Dostępny w: https://www.mdpi.com/2076-2615/16/6/930. DOI: 10.3390/ani16060930
  Abstract Cognitive dysfunction and neurodegenerative disorders represent an increasing clinical challenge in aging dogs and cats, while objective and minimally invasive biomarkers for early detection and disease monitoring remain limited. Tear film is a biologically active fluid reflecting both local and systemic processes and offers a practical, non-invasive source of potential biomarkers in geriatric veterinary patients. Proteomic analyses of canine and feline tear film have revealed a complex protein composition, including molecules involved in inflammation, oxidative stress, immune regulation, and cellular homeostasis—processes implicated in neurodegeneration. However, growing evidence from human and veterinary research emphasizes the importance of CNS-specific and mechanistically informative biomarkers, such as markers of axonal injury, synaptic degeneration, and glial activation, which may provide a more precise framework for interpreting peripheral proteomic alterations. This review summarizes current knowledge …
• Molecular analysis of inherited disorders of cornification in polish patients show novel variants and functional data and provokes questions on the significance of secondary findings. [AUT. KORESP.] KATARZYNA WERTHEIM-TYSAROWSKA, [AUT.] KATARZYNA OSIPOWICZ, KATARZYNA WOŹNIAK, JUSTYNA SAWICKA, ADRIANNA MIKA, ANNA KUTKOWSKA-KAŹMIERCZAK, KATARZYNA NIEPOKÓJ, AGNIESZKA SOBCZYŃSKA-TOMASZEWSKA, BARTŁOMIEJ WAWRZYCKI, ALDONA PIETRZAK, ROBERT ŚMIGIEL, BARTOSZ WOJTAŚ, BARTŁOMIEJ GIELNIEWSKI, ALICJA SZABELSKA-BERESEWICZ, JOANNA ZYPRYCH‑WALCZAK, AGNIESZKA M. RYGIEL, ALICJA DOMASZEWICZ, NATALIA BRAUN-WALICKA, ALICJA GRABARCZYK, SYLWIA RZOŃCA-NIEWCZAS, LIDIA RUSZKOWSKA, MATEUSZ DAWIDZIUK, DOMINIK DOMAŃSKI, TOMASZ GAMBIN, MONIKA JACKIEWICZ, KATARZYNA DUK, BARBARA DOROŻKO, OREST SZCZYGIELSKI, NATALIA KRZEŚNIAK, BARTŁOMIEJ H. NOSZCZYK, EWA OBERSZTYN, JOLANTA WIERZBA, ARTUR BARCZYK, JENNIFER CASTANEDA, ANNA ECKERSDORF-MASTALERZ, ANNA JAKUBIUK-TOMASZUK, PAWEŁ WŁASIENKO, ILONA JASZCZUK, ALEKSANDRA JEZELA-STANEK, JAKUB KLAPECKI, MICHEL VAN GEEL, CEZARY KOWALEWSKI, JERZY BAL, ANTONI GOSTYŃSKI. Orphanet J. Rare Dis. [online] 2024 vol. 19 [art. nr] 413, s. 1-14, bibliogr. poz. 43, [przeglądany 20 listopada 2024]. Dostępny w: https://ojrd.biomedcentral.com/articles/10.1186/s13023-024-03395-4. DOI: 10.1186/s13023-024-03395-4
  Abstract Background The Mendelian Disorders of Cornification (MeDOC) comprise a large number of disorders that present with either localised (palmoplantar keratoderma, PPK) or generalised (ichthyoses) signs. The MeDOC are highly heterogenic in terms of genetics and phenotype. Consequently, diagnostic process is challenging and before implementation of the next generation sequencing, was mostly symptomatic, not causal, which limited research on those diseases. The aim of the study was to genetically characterise a cohort of 265 Polish patients with MeDOC and to get insight into the skin lesions using transcriptome and lipid profile analyses. Results We detected causal variants in 85% (226/265) patients. In addition to the primary gene defect, a pathogenic variant in another gene involved in MeDOC pathology was identified in 23 cases. We found …
• Optimization of supercritical CO₂ extraction of Petasites hybridus rootstocks using Box-Behnken design: yield modeling, chemical profiling, and evaluation of COX-2 inhibitory activity. [AUT. KORESP.] ŁUKASZ KULINOWSKI, [AUT.] ŁUKASZ PECIO, SIMON VLAD LUCA, ŁUKASZ KURACH, BERNARD PAWLAK, GRZEGORZ FLORKOWSKI, BARBARA BUDZYŃSKA, KRYSTYNA SKALICKA-WOŹNIAK. J. Supercrit. Fluids [online] 2026 vol. 235 [art. nr] 107005, s. 1-15, bibliogr, [przeglądany 7 maja 2026]. Dostępny w: https://www.sciencedirect.com/science/article/abs/pii/S089684462600121X. DOI: 10.1016/j.supflu.2026.107005
  Abstract Petasites hybridus extracts are valued for their antimigraine and anti-inflammatory properties but require pyrrolizidine alkaloids-free and compositionally consistent extraction methods. Supercritical CO₂ extraction offers an alternative to organic solvents, yet its performance for butterbur has not been systematically optimized or linked to chemical and biological outcomes. This study aimed to optimize extraction conditions using Box–Behnken design and evaluate extraction yield, sesquiterpenoid content, pyrrolizidine alkaloids levels, and cyclooxygenase-2 (COX-2) inhibitory activity across the investigated extraction conditions. Fifteen extracts were prepared across a three-factor Design of Experiments (DOE). Sesquiterpenoids and pyrrolizidine alkaloids were quantified using UPLC-PDA-MS/MS. COX-2 inhibition was assessed using a fluorometric screening assay. Data were modelled using response surface methodology and multivariate regression analysis. Extraction yield responded to temperature and CO₂ consumption, while sesquiterpenoid composition remained stable. Supercritical CO₂ …
• Integrated roles of hypoxia signaling, lipid-handling, and extracellular matrix remodeling genes in myocardial infarction and heart failure: a gene-centric translational review. [AUT.] RAFAŁ CELIŃSKI, JANUSZ KOCKI, ANNA GRZYWA-CELIŃSKA, [AUT. KORESP.] KATARZYNA DOS SANTOS SZEWCZYK, ANNA BERECKA-RYCERZ. Appl. Sci. [online] 2026 vol. 16 nr 10 [art. nr] 4806, s. 1-42, bibliogr. poz. 232, [przeglądany 12 maja 2026]. Dostępny w: https://www.mdpi.com/2076-3417/16/10/4806. DOI: 10.3390/app16104806
  Abstract Heart failure (HF) and myocardial infarction (MI) are interconnected syndromes with overlapping pathogenic pathways, including ischemia, neurohormonal activation, and maladaptive remodeling. Hypoxia-response genes, lipid-handling genes, and extracellular matrix (ECM) genes each influence these processes. Understanding their integrated roles can uncover biomarkers and targets. A systematic literature search was conducted (PubMed, Web of Science, and Scopus; 2000–2026; English-only, following PRISMA guidelines) to identify studies on key genes in hypoxia signaling, lipid metabolism, and ECM remodeling in MI/HF. Acute hypoxia (via HIFs) orchestrates metabolic adaptation and inflammation, but chronic HIF activation drives fibrosis and dysfunction. In parallel, genes controlling triglyceride and cholesterol handling (e.g., LPL, APOC3) influence energy supply and vascular risk. Variants in these genes modulate plasma lipids and MI/HF risk. For example, genetic loss-of-function in APOC3 lowers triglycerides and …
• New haplotype of Bartonella sp. in Haematopota pluvialis (Linnaeus, 1758). [AUT. KORESP.] KATARZYNA BARTOSIK, [AUT.] MAGDALENA ŚWISŁOCKA-CUTTER, JOANNA WERSZKO, ANNA AFTYKA, KLAUDIA M. ŠVIRLOCHOVÁ, DANA ZUBRIKOVÁ, BRONISLAVA VÍCHOVÁ, MAGDALENA RASZEWSKA-FAMIELEC, [AUT. KORESP.] MAREK ASMAN. Pathogens [online] 2026 vol. 15 nr 4 [art. nr] 417, s. 1-14, bibliogr. poz. 66, [przeglądany 22 kwietnia 2026]. Dostępny w: https://www.mdpi.com/2076-0817/15/4/417. DOI: 10.3390/pathogens15040417
  Abstract Haematopota pluvialis is a widely distributed hematophagic insect occurring across Eurasia. This horse fly may be a highly efficient mechanical vector of pathogens, including viruses, bacteria, and protozoa. Furthermore, its painful bites can cause local skin lesions and systemic symptoms. The aim of this study was to determine human exposure to H. pluvialis attacks in various types of open space habitats in Eastern Poland and to perform molecular screening of these tabanids for the presence of hematopathogens: Bartonella spp. and Anaplasma phagocytophilum. Specimens of H. pluvialis were collected at three distinct sites in Eastern Poland. The presence of Bartonella spp. and A. phagocytophilum was investigated using PCR-based methods. In total, 141 H. pluvialis females were analyzed. The molecular analysis of the rpoB gene fragment yielded one new haplotype of …